barrier technologies. Solid oral
dose packaging with COC- or
COP-based blister films has
achieved regulatory compliance
and commercial success in
major global markets, with new
applications constantly emerging.
These films also deliver an
extra level of performance in
the packaging of functional
devices, particularly those of a
large enough size that traditional
barrier materials such as PVDC
and PCTFE fail to retain their
barrier performance at the depth
of thermoforming required to
package the device.
Cyclic olefin materials are also
used in flexible packaging as
sealant layer components in the
packaging of pharmaceutical
ingredients that tend to readily
adsorb and permeate through
more common sealant resins.
A prime example is pouch
packaging of nicotine-containing
products such as patches.
The low adsorption of many
pharmaceutical compounds by
cyclic olefins enables potency to
be maintained, while enabling
conventional heat sealing for
maximum product protection.
This has become an especially
acute need with the impending
market withdrawal of sealant
films made from polyacrylonitrile
items are packaged in flexible,
thermoformed plastic packages
for shipping and handling. These
plastic films need to be durable
without adding excess weight
and cost. Polyethylene (PE) is
an inexpensive solution, but it is
not a high-performance material.
When PE is enhanced with
cyclic olefin resins, stiffness and
thermoforming performance are
improved in these applications.
Cyclic olefin/PE films can compare
favorably in both cost and
performance to packages made
with nylon or ionomer resins, as
well as PE-only films.
Other significant and growing
for cyclic olefin materials include
such as microfluidic devices for
analytical and diagnostic testing;
mold components for contact
lens manufacturing; and various
components of medical devices
ranging from optical scanners
to bone cement mixers used in
joint replacement procedures.
The unique properties of cyclic
olefin resins have enabled
development of a broad range
of pharmaceutical packaging
applications. As performance
and regulatory demands on
packaging grow ever more
difficult in the coming years,
cyclic olefin-based products will
continue to increase their share
of this important market.
SANITARY/USDA-ACCEPTED • PNEUMATIC CONVEYING COMPONEN TS & SYSTEMS
BATCH & CON TINUOUS OPERATION • MULTI-INGREDIEN T HANDLING SYSTEMS • BATCH WEIGHING & SCALING SYSTEMS
UL-CONTROLS & CON TROL PACKAGES • FDA-APPROVED/CERTIFIED MATERIALS OF CONSTRUCTION
Let us solve your pneumatic conveying
challenges. Visit vac-u-max.com/pneumatic
or call 800-VAC-U-MAX.
More than 60 years of custom application
experience in the pharmaceutical industry.
Over 10,000 different powder and bulk materials
handled—including Free-Flowing and Non-Free
Flowing Powders. Technical expertise including
FAT and SAT validation. And an airtight performance guarantee. It’s what makes VAC-U-MAX
as unique and trusted as the pharmaceutical
process automation solutions we design.
From sanitary components to fully automated
batch or continuous systems, we create
pharmaceutical processing solutions
entirely around your needs and goals.
VAC-U-MAX Gel Cap, Capsule, and Coated
Tablet Conveyor for Gentle Delivery of Product
to Capsule Filling or Packaging Machines