The new standard in HPMC capsules:
Immediate release in-vivo performance
bioequivalent to gelatin and consistent
dissolution across changing pH and
Vcaps® Plus capsules can optimize capsule disintegration for pharmaceutical
products with the ability to release contents independent of pH and ionic
strength of the test media. And a new in-vivo study demonstrates that
Vcaps Plus capsules are equivalent to gelatin in terms of human
Finally, a superior specialty polymer capsule with proven gelatin-like
performance without cross-linking potential, Vcaps Plus is the new capsule
standard with benefits of narrow weight variability, impressive resistance to
heat and humidity, and validated manufacturing experience. By reducing
variability, Vcaps Plus capsules are quickly becoming a powerful new tool to
reduce timelines in drug product development.
Contact us at 800-845-6973 for our full technical package and
samples for your development review.
New in-vivo results comparing Vcaps Plus HPMC
Capsules and gelatin capsules demonstrate
bioequivalency of HPMC in multiple dissolution profiles.
Time in minutes
pH 1. 2 USP
pH 6. 8 USP
pH 6. 8 JP2
Simulated milk fluid
pH 1. 2 – 2 g KCI/L
pH 1. 2 – 9 g KCI/L
In-vitro dissolution of caffeine in
Vcaps Plus capsules
True pH and Ionic Media Independence
Nominal Hours (hrs) Post Dose
024 6 81012
Molecule = Acetaminophen Human
cross-over study in 24 subjects
Mean in-vivo acetaminophen plasma
concentration profiles over 12 hours.
Proven Bioequivalence to Gelatin
Read the full report at VcapsPlus.com.
Not all capsules are
Vcaps® Plus Capsules