Above: PCT’s Mountain View, CA clean room.
Right: A Cell Therapy Specialist obtaining an aliquot for sample analysis.
company’s President and Chief Scientific Officer. Back in the
mid 1980’s, before there was a term for cell therapy or regenerative medicine, Preti began his career working for a small
start-up company. The company had been founded by two
post-docs who knew Preti from grad school. The company
was looking to grow bone marrow in a three-dimensional
manner and store it – much like cord blood and adult stem
cells are now stored.
Preti was tasked with devising a system to grow the bone
marrow, as bone marrow is not easy to harvest and only
a small amount can be collected at a time. The founders
reasoned that should they be able to expand the cells in
three dimensional constructs, these small amounts of cells
collected from young, healthy individuals could someday be
expanded and used for the donor in the event s/he required
a bone marrow transplant. As Preti explains, “We built these
constructs and we had some difficulty trying to get the process to work.” But in doing so, Preti and the team made another discovery – the constructs they were using to try and
grow bone marrow looked more like skin than bone marrow.
So they started another company, called Advanced Tissue
Sciences, and created a product called DermaGraft which is
still being sold today.
After this initial success, Preti’s career next took him to
the New York Blood Center where he worked on bone mar-
row transplantation at a time when this procedure was just
starting to be used for chemotherapy and radiation patients
Progenitor Cell Therapy (PCT), a cutting-edge contract de-
velopment and manufacturing organization with facilities in
Allendale, NJ, Mountain View, CA and Irvine, CA, is working
to help make tailor-made therapies a reality for a wide range
of patients. Through a combination of expertise, technolog-
ical achievements and business acumen, PCT is paving the
way in the field of cell therapy, a small subset of the phar-
Regenerative medicine and cell therapy is sometimes considered the fourth pillar of medicine alongside traditional pharmaceuticals, biologics, and medical devices. PCT holds a unique
position as a contract developer and manufacturer that is entirely focused on this rapidly growing market. PCT has evolved
alongside the relatively young cell therapy industry, and over its
past 15 years of operation, has acquired a wealth of expertise in
this market segment, emerging as a leader in the field.
HISTORY AND BACKGROUND
PCT’s history is tied directly to Robert Preti, Ph.D., the
■ By Mike Auerbach, Editor In Chief
PCT takes the lead in delivering cell therapy and regenerative medicine
Getting Very Personal: