Mobile Clean Room Design
Walker Barrier Systems has introduced an extended-width mobile
clean room with 1,350 square feet of workable space. All Walker
rooms include doors with windows, door closers, interlocks, adjustable sweeps, airlocks, cascading pressure operation between
rooms and dry chemical fire suppression systems.
Mammalian Culture Single-Use System
Sartorius Stedim Biotech has introduced Sartoclear
Dynamics, a clarification system featuring new
single-use technology for harvesting mammalian cell
cultures with high cell densities. Higher cell line concentrations place growing challenges on the purification process, and as body feed filtration has proved
to be the best solution to solve similar challenges
in related industries, Sartorius Stedim Biotech has
now developed technology for biotech applications.
Specially designed for cGMP processing, Sartoclear Dynamics consists of prefilled single-use bags containing ultrapure diatomaceous earth (DE) in a choice of 0.5 kg to 10
kg. With a new quick-connect adapter for dust-free powder transfer, DE can be directly
mixed into the cell culture fluid. This porous filter aid prevents filter blockage.
Aseptic Syringe Filling &
Dara SFL Syringe
Filling and Plugging machine,
an aseptic filling
syringes or vials
in a nest or tray.
Dara can equip
Dara SFL with an
access barrier (RAB) and a peristaltic
pump or valve-less rotary piston pump.
With its servo motion controls and
high quality engineering, the Dara SFL
offers filling and plunger insertion, faster
changeovers, less maintenance and
the flexibility to add package and tray
formats. This aseptic manufacturing
system fills and closes up to 35 units per
minute if equipped with one filling head
and one closing head and up to 80 units
per minute with two heads. It accommodates glass and plastic syringes with fill
volumes from 0.5 to 20 ml and vials with
fills volumes from 0.5 to 50 ml.
Centrifugal Impact Mill
A new pharmaceutical-grade Pin Mill, model CIM-
18-S316 from Munson Machinery, grinds friable
powders, flakes and granules into controlled particle
sizes ranging from coarse to fine. The outer and inner
discs can swing away from the unit on cantilevered
arms, providing full access to both sides of both discs
and the mill housing. High-speed rotation of the inner
disc creates centrifugal force that accelerates bulk
material entering the central inlet of the opposing
stationary disc. As material travels from the center
to the periphery of the discs at high speed, it passes
through a path of five intermeshing rows of precision-machined rotating and
stationary impactor pins, with the desired tight particle size distribution obtained by controlling the rotor speed. Constructed of #316 stainless steel, the
unit features a sanitary butterfly valve on the air intake, sanitary fittings at the
material intake and discharge and a wash-down-duty motor.