Left to right: Norwich offers comprehensive product development capabilities with R&D, GMP
pilot scale manufacturing, analytical development and validation, and testing services.
Norwich employs cutting-edge technologies to satisfy a wide spectrum of project demands,
including products that are difficult to manufacture.
Product Development & Technical Services staff, equipment and facilities are dedicated to serve
all of your manufacturing and packaging needs for small to mid-scale development, clinical
supply and stability programs.
• The pilot scale facility’s equipment
and technology mirror commercial scale capabilities, allowing
for direct transfer from analytical
to quality control.
• In the last 12 months, Norwich has nearly
tripled its pilot-unit capacity to a total of
19 rooms. Each has the ability to handle
Occupational Exposure Limits (OELs) for
drug potencies ranging from category one to three.
• All manufacturing suites are equipped with HEPA filters to
prevent cross-contamination between rooms. For maximum
environmental control, a Honeywell® system tracks pressure differentials, temperature, and humidity levels throughout the manufacturing and warehouse facilities.
• Some of the newer technologies being tested in the pilot
scale facility include laser drilling for osmotic delivery,
tablet in capsule and bi-layer compression.
• Fluid granulation capacity has been expanded, along with
low-humidity manufacturing and packaging in order to match
the pilot unit’s capabilities. Ultimately, the goal is to take all
the equipment and technology from the pilot scale operation
and emulate it on the commercial manufacturing side of the
business in providing customers a seamless scale-up. Low hu-
midity capabilities have been expanded to handle products down to a 30 percent humidity environment.
• On the commercial manufacturing
side, Norwich has expanded their
blending technology options by
adding bin blending to match their
pilot-unit capabilities. Many newer prod-
ucts are being processed using bin-blenders
because they offer the potential for better uni-
formity and the ability to overcome obstacles in
• Packaging capabilities have been expanded, with speeds
improving 25-50 percent, depending on bottle size. ■