Single-Use, Rocking Bioreactor System ;
The ReadyToProcess WAVE™ 25 bioreactor system is
designed to meet the evolving needs of bioprocessing. The
system allows precise, automated, and intelligent control
of numerous process parameters through a user-friendly
graphical operator interface, which provides real-time
control and many data analysis and reporting options.
The system is suitable for research, process development, and biopharmaceutical manufacturing
applications. The complete system comprises a rocker, gas mixer, and pump, all
operated by UNICORN™ control software. The system supports the use
of disposable Cellbag™ bioreactor
cultivation chambers with working volumes of up to 25 L. Set-up
is quick as suitable parameters can
be automatically determined for the run using a library of predefined controls tailored for
different cultivation volumes. In addition, Ready ToProcess WAVE 25 automatically monitors
culture conditions and rapidly responds to changes to optimize performance, providing
accurate and stable control of the process. The UNICORN software supports use in a manner
that complies with 21 CFR Part 11 and good automated manufacturing practice (GAMP). The
software allows remote control and the optional setting of alarm conditions for essential
parameters including heating, gas flow, carbon dioxide, pH and dissolved oxygen, for reliable
cell culture operations. ■ GE Healthcare Bio-Sciences, Piscataway, NJ 08855.
www.gelifesciences.com or call 800-526-3593
; Biopharmaceutical Mixing
Allegro single-use mixers are part of the company's expanding range of Allegro products
and services providing integrated process
solutions throughout the drug production
process. The Allegro mixers combine critical
requirements for single-use technologies,
such as extreme ease-of-use, with established
engineering principles and criteria for robust
mixer design to deliver the ultimate in mixing
performance. ■ Pall Life Sciences, Port Washington, NY 11050. www.Pall.com/biopharm or
Vcaps® Plus hypromellose capsules for pharmaceutical products
Secondary gelling agents and ionic gel promoters – used by other
HPMC capsules – may slow down release of active ingredients.
Capsugel’s Vcaps® Plus HPMC capsules are made through a proprietary
manufacturing process that eliminates the need for gelling systems.
They disintegrate and release their contents independent of pH and ionic
strength of the test media. Download our free whitepaper to discover
how Vcaps® Plus capsules can optimize performance, improve product
stability, and reduce drug development times.
Achieving new standards in performance takes
years of innovative R&D. This is the result.